Ogasiti 17, 2015 |Zida ndi zida, Zida za labotale ndi zida za labotale, Nkhani za labotale, Njira zama labotale, Matenda a Laboratory, Kuyesa kwa labotale
Poyika chipangizochi chotsika mtengo chogwiritsira ntchito chimodzi, chopangidwa ku yunivesite ya Wisconsin-Madison, pa mkono kapena pamimba, odwala amatha kutenga magazi awo kunyumba mumphindi.
Kwa zaka zopitirira ziwiri, atolankhani aku America achita chidwi ndi lingaliro la CEO wa Theranos Elizabeth Holmes kuti apatse odwala omwe akufunika kuyezetsa magazi kuyezetsa magazi ndi chala m'malo mwa venipuncture.Pakadali pano, ma laboratories ofufuza m'dziko lonselo akuyesetsa kupanga njira zosonkhanitsira zitsanzo zoyezetsa ma labu azachipatala omwe safuna singano konse.
Ndi khama loterolo, likhoza kulowa mumsika mofulumira kwambiri.Ichi ndi chipangizo chamakono chosonkhanitsira magazi chopanda singano chotchedwa HemoLink, chopangidwa ndi gulu lofufuza pa yunivesite ya Wisconsin-Madison.Ogwiritsa amangoyika chipangizo cha gofu pa mkono kapena m'mimba mwawo kwa mphindi ziwiri.Panthawi imeneyi, chipangizocho chimatulutsa magazi kuchokera ku capillaries kupita ku chidebe chaching'ono.Wodwalayo amatumiza chubu la magazi osonkhanitsidwa ku labotale yachipatala kuti akawunike.
Chipangizo chotetezeka ichi ndi chabwino kwa ana.Komabe, odwala omwe amafunikira kuyezetsa magazi pafupipafupi kuti awone thanzi lawo amapindulanso chifukwa zimawapulumutsa ku maulendo pafupipafupi kupita ku ma laboratories azachipatala kuti akatenge magazi ndi njira yachikhalidwe yobaya singano.
Munjira yotchedwa "capillary action," HemoLink imagwiritsa ntchito ma microfluidics kupanga vacuum yaying'ono yomwe imatulutsa magazi kuchokera ku ma capillaries kudzera munjira ting'onoting'ono pakhungu kupita ku tubules, Gizmag malipoti.Chipangizocho chimasonkhanitsa ma kiyubiki masentimita 0,15 a magazi, omwe ndi okwanira kuti azindikire cholesterol, matenda, maselo a khansa, shuga wamagazi ndi zina.
Akatswiri azachipatala komanso akatswiri azachipatala aziwonera kukhazikitsidwa komaliza kwa HemoLink kuti awone momwe opanga ake amagonjetsera zovuta zomwe zimakhudza kulondola kwa mayeso a labotale omwe amatha chifukwa chamadzi am'kati omwe nthawi zambiri amatsagana ndi magazi a capillary akamatola zitsanzo zotere.Momwe ukadaulo woyezera ma labu wogwiritsidwa ntchito ndi Theranos ungathetsere vuto lomwelo wakhala cholinga cha ma labu azachipatala.
Tasso Inc., chiyambi chachipatala chomwe chinapanga HemoLink, chinakhazikitsidwa ndi akatswiri atatu akale a UW-Madison microfluidics:
Casavant akufotokoza chifukwa chake mphamvu ya microfluidic imagwira ntchito: "Pakali pano, kugwedezeka kwa pamwamba n'kofunika kwambiri kuposa mphamvu yokoka, ndipo kumasunga magazi mumsewu mosasamala kanthu kuti mutagwira bwanji chipangizocho," adatero Gizmag lipoti.
Ntchitoyi idathandizidwa ndi $ 3 miliyoni ndi Defense Advanced Research Projects Agency (DARPA), gulu lofufuza la United States Department of Defense (DOD).
Oyambitsa atatu a Tasso, Inc., omwe kale anali ofufuza a microfluidics ku yunivesite ya Wisconsin-Madison (kuchokera kumanzere kupita kumanja): Ben Casavant, Wachiwiri kwa Purezidenti wa Operations and Engineering, Erwin Berthier, Vice Prezidenti wa Research and Development and Technology, ndi Ben Moga, Purezidenti, mu shopu ya khofi adapanga lingaliro la HemoLink.(Zokonda pazithunzi Tasso, Inc.)
Chipangizo cha HemoLink ndi chotsika mtengo kupanga ndipo Tasso akuyembekeza kuti azitha kupezeka kwa ogula ku 2016, malinga ndi Gizmag.Komabe, izi zingadalire ngati asayansi a Tasso angathe kupanga njira yotsimikizira kukhazikika kwa zitsanzo za magazi.
Pakalipano, zitsanzo zambiri zamagazi zoyezetsa zachipatala za labotale zimafunikira zoyendera mu unyolo wozizira.Malinga ndi lipoti la Gizmag, asayansi a Tasso akufuna kusunga magazi pa madigiri 140 Fahrenheit kwa sabata kuti awonetsetse kuti ayesedwa akafika ku labu yachipatala kuti akakonze.Tasso akufuna kulembetsa chilolezo cha US Food and Drug Administration (FDA) kumapeto kwa chaka chino.
HemoLink, chipangizo chotsika mtengo chotaya magazi opanda singano, chikhoza kupezeka kwa ogula mu 2016. Amagwiritsa ntchito njira yotchedwa "capillary action" kuti atenge magazi mu chubu chosonkhanitsa.Ogwiritsa ntchito amangoyiyika pa mkono kapena m'mimba mwawo kwa mphindi ziwiri, kenako chubucho chimatumizidwa ku labu yachipatala kuti aunike.(Zokonda pazithunzi Tasso, Inc.)
HemoLink ndi nkhani yabwino kwa anthu omwe sakonda ndodo za singano ndi olipira omwe amasamala za kuchepetsa ndalama zothandizira zaumoyo.Kuonjezera apo, ngati Tasso ipambana ndikuvomerezedwa ndi FDA, ikhoza kuperekanso anthu padziko lonse lapansi - ngakhale kumadera akutali - kuti athe kulumikizana ndi ma laboratory oyesa magazi apakati ndikupindula ndi matenda apamwamba.
"Tili ndi deta yokakamiza, gulu loyang'anira mwaukali komanso zosowa zachipatala zomwe sizikukwaniritsidwa pamsika womwe ukukula," adatero Modja mu lipoti la Gizmag."Kukulitsa chisamaliro chapakhomo ndi kusonkhanitsa magazi otetezeka komanso osavuta kuti adziwe matenda ndi kuwunika ndi mtundu wazinthu zatsopano zomwe zingapangitse zotulukapo zake popanda kuonjezera ndalama zachipatala."
Koma si onse omwe ali nawo mumakampani azachipatala omwe angasangalale ndi kukhazikitsidwa kwa msika wa HemoLink.Ndiukadaulo womwe ungathe kusintha masewera m'ma laboratories azachipatala komanso kampani ya Silicon Valley biotech ya Theranos, yomwe yawononga madola mamiliyoni ambiri kukonza momwe imayezetsa magazi movutikira kuchokera ku zitsanzo zamagazi, USA TODAY lipoti.
Zingakhale zodabwitsa ngati opanga HemoLink atha kuthetsa vuto lililonse ndiukadaulo wawo, kupeza chilolezo cha FDA, ndikubweretsa kugulitsa malonda mkati mwa miyezi 24 yotsatira yomwe imathetsa kufunikira kwa venipuncture ndi sampuli zala.Mitundu yambiri ya mayeso a labotale azachipatala.Izi ndizotsimikizika kuba "bingu lopambana" kuchokera ku Theranos, lomwe kwa zaka ziwiri zapitazi lakhala likuwonetsa masomphenya ake kuti asinthe makampani oyesa zachipatala momwe akuchitira lero.
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Sindikudziwa momwe izi zimagwirira ntchito - Theranos samatulutsa zambiri.M'masiku angapo apitawa, alandilanso zidziwitso zosiya ndi kuletsa.Kumvetsetsa kwanga pazidazi ndikuti zimagwiritsa ntchito "ma clumps" amphamvu kwambiri a ma capillaries omwe amakhala ngati singano.Zikhoza kusiya zowawa pang'ono, koma sindikuganiza kuti kulowa kwa khungu kumakhala kozama ngati singano (mwachitsanzo Akkuchek).